10 Best Audio Interfaces With MIDI Ports for 2026: Top Picks for Home Studios, Musicians, and Producers

If you need an audio interface with MIDI ports, you’re likely balancing recording quality, instrument inputs, and hands-on control for a small studio setup. The right model should make it easy to track vocals, guitars, keyboards, and hardware synths without adding friction.

In this roundup, we focus on interfaces that pair solid audio performance with practical MIDI connectivity, so you can build a streamlined setup that works now and scales later.

Best 10 Audio Interface with Midi Ports Picks for 2026

Best Budget Pick – Behringer U-PHORIA UMC404HD 4×4 USB Audio/MIDI Interface

If you want an audio interface with midi ports that gives you plenty of I/O without pushing the budget too far, the Behringer U-PHORIA UMC404HD is a straightforward pick. It offers 4×4 USB audio/MIDI connectivity, 24-bit/192 kHz recording, and Midas-designed mic preamps, so it covers basic home-studio tracking with a practical feature set.

Best For: Home recordists who need 4 inputs, MIDI I/O, and a rugged interface for everyday sessions.

Pros:

• 4×4 USB 2.0 audio/MIDI interface with 1 MIDI I/O
• 24-bit/192 kHz resolution for high-quality recording
• 4 MIDAS-designed mic preamps with +48V phantom power
• Impact-resistant metal chassis built for durability

Cons:

• Uses USB 2.0 rather than newer USB-C connectivity
• Bulkier than compact 2-channel interfaces

Overall, this is a practical option if you need multiple inputs and MIDI support in a durable box. It leans more toward utility than bells and whistles, which is exactly what many first-time and budget-minded setups need.

Best Overall – Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface

The Focusrite Scarlett 4i4 4th Gen is a strong audio interface with midi ports for musicians who want a flexible, modern recording hub. It combines two 4th Gen mic preamps, two Hi-Z instrument inputs, four line inputs, four line outputs, and MIDI I/O, making it a versatile choice for mics, guitars, synths, and drum machines.

Best For: Musicians who want a polished all-in-one interface for recording, playback, and MIDI gear.

Pros:

• Two 4th Gen mic preamps plus two Hi-Z inputs
• 4 line inputs and 4 line outputs with MIDI I/O
• 120 dB dynamic range and 24-bit/192 kHz support
• Auto Gain, Clip Safe, and Air mode for easier recording

Cons:

• Designed as a 4-channel hub, not a larger multitrack interface
• Feature-rich setup may be more than basic users need

This model stands out for balancing sound quality, workflow tools, and broad gear compatibility. If you want an interface that feels ready for serious home-studio work, the 4i4 is an easy one to consider.

Best Portable Pick – Mackie Onyx Producer 2X2 USB Audio Interface

If you need an audio interface with midi ports in a compact, bus-powered design, the Mackie Onyx Producer 2X2 keeps things simple. It delivers 2-in/2-out 24-bit/192 kHz recording, MIDI I/O, and two Onyx mic preamps, making it a solid fit for small setups and mobile recording.

Best For: Solo artists and mobile recordists who want a lightweight interface with MIDI support.

Pros:

• 2-in/2-out USB interface with MIDI I/O
• 24-bit/192 kHz recording with two Onyx mic preamps
• Bus-powered, so no power adapter is required
• Zero-latency direct monitoring with dedicated outputs

Cons:

• Only two inputs and two outputs
• Less suitable for larger tracking sessions

The Onyx Producer 2X2 is a practical choice when portability matters more than channel count. It gives you the essentials for recording, monitoring, and MIDI integration without adding complexity.

Best USB-C Pick – MOTU M4 4×4 USB-C Audio Interface

The MOTU M4 is a strong audio interface with midi ports for users who want modern USB-C connectivity and a flexible 4×4 layout. It includes two microphone preamps, MIDI I/O, hardware monitoring, and a front LCD screen, so it works well for recording, mixing, and podcasting.

Best For: Creators who want a compact USB-C interface with MIDI I/O and clear monitoring feedback.

Pros:

• 4-in/4-out USB-C audio interface with MIDI I/O
• Two microphone preamps for recording vocals or instruments
• Hardware monitoring and LCD screen for easier level checks
• Includes 6+GB of free content for Mac, PC, and iOS

Cons:

• No power supply details are included in the supplied notes
• Software bundle is aimed at basic production use

This is a good fit if you want a compact interface that feels modern and easy to monitor at a glance. The M4 keeps the feature set focused while still covering recording, mixing, and MIDI workflows.

Compact Creator Pick – Arturia MiniFuse 1 USB Audio & MIDI Interface

If you want an audio interface with midi ports that stays simple without cutting useful features, the Arturia MiniFuse 1 is built for exactly that kind of setup. It combines a compact USB recording workflow with 5-pin MIDI in and out, so you can connect synths, controllers, and drum machines alongside mics and instruments.

Best For: Bedroom producers, singer-songwriters, and beginners who want easy MIDI connectivity plus bundled software.

Pros:

• Includes 5-pin MIDI input and output for hardware synths and controllers
• Compact design with USB workflow and a built-in USB-A hub
• Mic, instrument, and line connectivity with 48V phantom power
• Backed by a 5-year warranty and 200+ reliability tests

Cons:

• Only 1 input channel, so it is limited for multi-source tracking
• Smaller footprint means fewer simultaneous recording options

The MiniFuse 1 is a practical choice if your focus is music creation rather than heavy tracking. Its MIDI ports and included software make it especially appealing for first-time buyers who want a straightforward way to connect modern and vintage gear.

Precision Monitoring Pick – MOTU M2 USB-C Audio Interface

The MOTU M2 is a smart pick if you want an audio interface with midi ports-style hardware flexibility, but your main priority is clean 2-in/2-out recording and reliable monitoring. It is a USB-C interface with hardware monitoring, 24-bit/192kHz support, and two preamps for straightforward recording setups.

Best For: Users who want a compact, high-resolution interface for focused recording and monitoring.

Pros:

• 2 preamps and 2-in/2-out layout for simple recording workflows
• Hardware monitoring helps reduce latency while tracking
• 24-bit/192kHz operation for high-resolution audio capture
• USB-C connectivity with macOS, Windows, and iOS support listed in the notes

Cons:

• No MIDI ports are listed in the supplied notes
• Less suited to gear-heavy setups that need external MIDI hardware

For buyers who mainly need excellent audio performance in a small interface, the M2 keeps things focused and practical. It stands out for monitoring and recording quality, but it is not the right pick if MIDI connectivity is a must-have.

Solo Recording Pick – Focusrite Scarlett Solo 3rd Gen USB-C Audio Interface

The Focusrite Scarlett Solo 3rd Gen is a clean, easy-to-use audio interface for solo recording, but it does not include MIDI ports. If your setup centers on one mic and one instrument, it offers the kind of polished, straightforward workflow that suits home recording, podcasts, and simple music production.

Best For: Solo musicians and podcasters who want dependable recording quality without MIDI needs.

Pros:

• High-performing mic preamp with switchable Air mode for extra clarity
• One XLR mic input plus one Hi-Z instrument input for guitar or bass
• 24-bit/192kHz converters for detailed recording and playback
• Includes a software bundle and a 3-year warranty

Cons:

• No MIDI ports are listed in the supplied notes
• Limited to a very simple input layout for expanding setups

This model makes sense when your priority is recording one source at a time with strong preamp quality and dependable monitoring. It is best viewed as a focused starter interface rather than a MIDI-capable hub.

Portable MIDI Recording Starter – PreSonus AudioBox 96 25th Anniversary USB Audio Interface

If you want an audio interface with midi ports for a simple home or portable setup, the PreSonus AudioBox 96 keeps things straightforward. It offers 2 channels, dual Class-A mic preamps, instrument inputs, and MIDI I/O, plus bus-powered USB 2.0 operation so you can record without carrying an extra power supply.

Best For: Musicians who want a budget-friendly 2-channel interface with MIDI I/O, bundled software, and easy mobile recording.

Pros:

• Includes MIDI I/O alongside 2 mic preamps and 2 instrument inputs
• USB bus-powered design makes it easy to use on the go
• 24-bit/96 kHz converters support solid recording and playback quality
• Comes with a large software bundle, including Studio One Artist and Ableton Live Lite

Cons:

• Limited to 2 channels, so it is not ideal for larger recording setups
• Uses USB 2.0 rather than newer USB-C connectivity

Overall, this is a practical entry point if you need MIDI connectivity, dependable basics, and a portable recording package. Its strength is value: the hardware is simple, and the included software adds a lot for first-time recordists.

Budget Streaming Interface – M-AUDIO M-Track Duo USB Audio Interface

The M-AUDIO M-Track Duo is a compact audio interface with midi ports built for simple recording, streaming, and podcasting workflows. It does not include MIDI connections, but it gives you two combo inputs, transparent preamps, zero-latency monitoring, and broad device compatibility for a fuss-free desktop setup.

Best For: Podcasters, streamers, and beginners who want a low-cost 2-channel interface with easy monitoring.

Pros:

• Two combo XLR/line/instrument inputs support a flexible range of sources
• USB/Direct switch enables zero-latency monitoring
• 48 kHz recording resolution is suitable for everyday content creation
• Includes MPC Beats software for basic production work

Cons:

• No MIDI I/O, so it is not a true fit if MIDI ports are required
• 48 kHz maximum sample rate is lower than higher-end recording interfaces

This is a solid pick for straightforward audio capture, but buyers specifically looking for an audio interface with midi ports should look elsewhere. Its strengths are simplicity, portability, and an easy learning curve for entry-level recording tasks.

Songwriter's Studio Pick – Focusrite Scarlett Solo 4th Gen USB-C Audio Interface

The Focusrite Scarlett Solo 4th Gen is a streamlined audio interface with midi ports? Not quite—it focuses on one mic preamp and one Hi-Z instrument input rather than MIDI connectivity. For solo songwriting, though, it brings 24-bit/192 kHz recording, a wide dynamic range, and an improved Air mode that adds presence to vocals and guitars.

Best For: Solo musicians who want compact, studio-quality recording for vocals and guitar.

Pros:

• High-end 120 dB dynamic range and 24-bit/192 kHz support
• Air mode adds extra presence and harmonic drive to recordings
• Compact USB-C design fits small desktop setups
• Includes Pro Tools Intro+, Ableton Live Lite, and Cubase LE

Cons:

• No MIDI I/O, so it is not suited to keyboard or rack MIDI setups
• Only one mic input and one instrument input, limiting multi-source recording

For singers and guitarists, this is a polished, modern interface with strong conversion and a useful vocal shaping feature. If MIDI ports are essential, it is not the right match, but as a compact solo-recording tool it is very capable.

How We Picked the Best Audio Interface with Midi Ports

We looked for an Audio Interface with Midi Ports that delivers a useful mix of sound quality, dependable drivers, enough I/O for common recording tasks, and a layout that makes day-to-day use simple. We also favored models that suit real-world home studio workflows, not just spec sheets.

Quick Comparison: What Matters Most

Some buyers need two clean inputs for vocals and instruments, while others want more line inputs for synths, drum machines, or outboard gear. USB-C models often offer easier modern connectivity, but the best choice still depends on your channel count, monitoring needs, and whether MIDI DIN ports are essential for your setup.

Key Buying Factors for an Audio Interface with Midi Ports

Inputs and Outputs

Match the interface to your workflow. Solo singers and guitarists can get by with compact units, but producers using keyboards or external processors may want extra line inputs and dedicated monitor outputs.

MIDI Connectivity

Check whether you need full-size 5-pin MIDI In and Out, since not every compact interface includes both. If you use hardware synths, drum machines, or external controllers, MIDI ports can save you from relying on separate adapters.

Sound Quality and Preamps

Clean preamps, low-noise performance, and solid gain staging matter more than flashy extras. If you record dynamic microphones or quiet sources, better preamps can make a noticeable difference.

Latency and Software Support

Low-latency monitoring and stable drivers are crucial for tracking without delay. Good software bundles can be helpful, but reliable performance should come first.

Who Should Buy Which Audio Interface with Midi Ports?

Choose a compact 2-in/2-out model if you mainly record one source at a time and only need basic MIDI integration. Step up to a 4-in/4-out interface if you track multiple instruments, route hardware synths, or want more flexibility for future expansion. For first-time buyers, prioritize simplicity and stable performance; for experienced producers, focus on I/O count, MIDI routing, and monitoring options.

Ultimately, the best Audio Interface with Midi Ports is the one that fits your studio size, your instruments, and the way you actually record every day.